- Los Árboles (The Trees) – Christmas Tree Forest, 2012, Art Museum of South Texas
- El Baile (The Dance) – Pepe Serna, No Place Like Home, serigraph, 1997, 33″ x 32″
- Las Ballenas (The Whales) – Kent Ullberg, Making Waves II, bronze sculpture, Gift of the Cora T. Keeler Estate
- El Bisonte (The Bison) – Kent Ullberg, Running Bison, lost wax bronze casting, 2008, 84″ x 38″ x 142″, Gift of Julie Buckley and John Buckley, Joan L. and Bernard A. Paulson, Carolyn and Dan Pedrotti, Laurie and Phillip Plant
- Los Botas (The Boots) – William Wilhelmi, Texas Boots, porcelain, 1979, 15.5″ x 3.75″ x 11″, Gift of Anthony Langford Feher
- El Caballero (The Cowboy) – William Schenck, Staked Plains, impervo enamel on canvas, 1971, 84″ x 78″, Gift of Dr. and Mrs. J.L. Silverman
- La Calavera (The Skull) – Luis Jiménez, Self Portrait, lithograph, n.d., 52″ x 42″, Gift of Carlota and John Robertson
- El Callejón (The Alley) – Joe Peña, Heaven’s Back Alley, oil on panel, 2005, 12″ x 16″
- El Cantarito (The Clay Cup) – Ron Boling, Raku Tea Pot, ceramic, 2007, 10.25″ x 10″ x 6.75″, Gift of Ron Boling
- La Cara (The Face) – James Surls, Seeing Through the Wind, bronze sculpture, 1997, 139″ x 54″ x 51″, Gift of the Rusty McMains Family
- Las Cebollas (The Onions) – Landon Curry, Still Life, 1987, 29″ x 21.5″, Gift of Connie C. Curry
- Los Círculos (The Circles) – Misha Gordin, The Polka Dot Sidewalk, gelatin silver print, 1986, 19.62″ x 19.62″, Gift of Misha Gordin and Jun Kaneko
- El Colorado (The Red One) – Pio Pulido, Untitled, serigraph, 1994, 22″ x 15.25″, Museum purchase funded by the Auxiliary of the AMST
- Los Colores (The Colors) – Dorothy Hood, Untitled, oil on canvas, late 1980s, 96.25″ x 120.25″ x 1.25″
- El Corazón (The Heart) – Mauro Garza, El Mundo de Corazón, serigraph, 1996, 25.75″ x 22.125″
- La Dama (The Lady) – Artist Dorothy Hood, 1940s, Mexico City
- El Edificio (The Building) – Dennis Blagg, Courthouse, oil on canvas, 1985, 98″ x 144″, Gift of JPMorgan Chase
- Las Flores (The Flowers) – Jim Love, Flowers, “found” steel, cast iron sculpture, 1997, 18.5″ x 15″ x 14″, The Friends of Jim Love
- El Gato (The Cat) – Norma McManaway, Gold Cat, ceramic, c.1970, 6″ x 8″ x 10″, The Barrett Collection, Dallas, TX, Gift of the Dallas Museum of Art
- El Grito (The Scream/Cry) – Carlos Gomez, Llanto, serigraph, 2000, 29.125″ x 21.25″
- La Guitarra (The Guitar) – Ricardo Ruiz, Baby Baby Sweet Baby, oil on canvas, 1990, 36″ x 48″, Purchase funded by Corpus Christi Art Foundation
- El Jugador (The Player) – Lance Richbourg, Paul Derringer, watercolor on paper, 1987, 67″ x 52″, Gift of Dr. John FitzGibbon
- Las Líneas (The Lines) – Dan Christensen, Musca, acrylic on canvas, 1968, 100.5″ x 140″, Gift of Philip Johnson
- El Lowrider (The Lowrider) – Luis Jiménez, El Corazón Lowrider, lithograph, 1997, 24″ x 36″
- El Luchador (The Wrestler) – Quintin Gonzalez, Chicano 15, serigraph, 2008, 16″ x 22″
- La Luna (The Moon) – Alexander Calder, La Lune et la Montagne Jaune, lithograph, 1960, 23.5″ x 19″, Gift of Mrs. Chela Storm
- Las Manos (The Hands) – Judy Chicago, Grand Hands of Choice, cast glass sculpture, 2007, 7.5″ x 20″ x 3.5″, Gift of the AMST 2010 Collectors Club
- El Marlín (The Marlin) – Al Barnes, Wrapped, But Not Delivered, acrylic on board, c. 2005, 22″ x 30″, Gift of Meredith Long & Co., Inc.
- La Mater (The Mother) – Unknown Mexican Artist, Mater Dolorosa, oil on canvas, c. 1800, 30″ x 26″, Gift of the Collectors Club
- Las Medusas (The Jellyfish) – John Alexander, Jellyfish, oil on paper, 2014, 30″ x 22″, Purchased with funds provided by the 2017 Collectors Club
- La Mona Lupe (The Mona Lupe) – César Martinez, Mona Lupe: The Epitome of Chicano Art, acrylic on canvas, 1992, 64″ x 54″, Museum purchase funded by the Corpus Christi Art Foundation
- El Mono (The Monkey) – Marjorie Moore, Stand-Up Sock, pencil on paper, 1995, 29.5″ x 22″
- El Moto (The Motorcycle) – Tom Blackwell, Triumph Trumpet, serigraph, 1981, 28.75″ x 28.75″, Gift of Louis K. Meisel Gallery
- El Museo (The Museum) – Art Museum of South Texas Complex
- La Noche (The Night) – Ansel Adams, Moonrise, Hernandez, New Mexico, gelatin silver print, 1941, 16″ x 20″, Gift of Libby Averyt and Charles Kaffie
- Las Nubes (The Clouds) – Linda Rodriguez, digital photo, 2019
- El Océano (The Ocean) – Deborah Brown, Olympic, oil on canvas, 1990, 78″ x 86″, Gift of the Artist
- Los Ojos (The Eyes) – Helen Oji, Multicultural, oil on canvas, 1994, 60″ x 72″, Gift of John F. Fitzgibbon
- Los Pajaros (The Birds) – Billy Hassell, After the Rain, oil on canvas, 2007, 60″ x 72″, Gift of Mesteña, L.L.C. in Memory of Lorine Eshleman Vogt, William T. Vogt, Sr., Jeanne Jones Hause and Florence
- El Pastel (The Cake) – William Wilhelmi, Happy Birthday Mom, earthenware, 1972, 12.5″ x 15″ x 15″, Gift of Wilhelmi-Holland Gallery in Memory of Florence Valentine Kaffie
- Las Perlas (The Pearls) – Jean Honore Fragonard, Girl with a Pearl Necklace: Portrait of Rosalie Fragonard, oil on canvas, c. 1785-88, 22.75″ x 18.75″, Gift of Mrs. John A. King
- El Perro (The Dog) – Robert Jessup, Jack, oil on canvas, 1999, 40.25″ x 40.25″, Purchased with funds from the Frances Cain Estate
- Las Pirámides (The Pyramids) – Legorreta Building, Art Museum of South Texas exterior
- La Plata (Silver) – unknown artist, Crucifix and Round Base, silver, c.19th Century, Gift of Nelwyn and John Anderson
- El Puente (The Bridge) – Amanda Horne, black and white photo, 2000
- El Pulpo (The Octopus) – Deborah Brown, Octopus II, oil on canvas, 1998, 30″ x 54″, Gift of the artist
- Las Ramas (The Branches) – Michael Christian, Self Portrait with Fan, wood and mixed media, 1989, 60″ x 48″ x 48″, The Barrett Collection, Gift of the Museum of Fine Arts, Houston
- La Rana (The Frog) – David Gilhooly, Tex-Mex Frog Plate, ceramic, 1991, 3.75″ x 11″, Gift of Mr. and Mrs. John Chapman
- Las Rayas (The Stripes) – Betty Mobley, Girl with Cats, oil on canvas, 1994, 48″ x 36″, Funding provided by Daryl and George Tanner
- El Reloj (The Clock) – Salvador Dali, Untitled, lithograph, n.d., 21.625″ x 21.25″, Gift of Ann Harithas
- La Sala (The Living Room) – Danny O’Dowdy, Divan, wood, felt, acrylic, steel wire, 1986, 64.5″ x 79″ x 36.5″, Gift of the Estate of Kenneth Holmes
- El Saxofon (The Saxophone) – Ricardo Ruiz, CuCuCuRuCu Cantava, oil on canvas, 1990, 30″ x 39.75″, Purchase funded by the Corpus Christi Art Foundation
- La Serpiente (The Snake) – Robert Willson, Pretty Serpent, glass sculpture, 1997, 20″ x 20″, Gift of Marsha and Cliff Larsen in memory of John and Zona Hansbrough
- Las Sillas (The Chairs) – Riley Robinson, WalMart-K-Mart, aluminum and aluminum chairs, 2000, 65″ x 65″, Gift of the artist
- La Sirena (The Mermaid) – Alma Lopez, El Vals de las Mariposas, serigraph, 2008, 16″ x 21.75″
- El Sofá (The Sofa) – Danny O’Dowdy, Laps and Layers, limestone and mosaic tile, 2004, 40″ x 84″ x 48″, Gift of Cornelia Freeman
- El Sol (The Sun) – Mary Ann Ambray Gonzales, When Day Holds Night in Gentle Caress, serigraph, 1993-94, 22″ x 16″, Museum purchase funded by the Auxiliary of the AMST
- Los Sombreros (The Hats) – Henry Medrano, Danzantes, serigraph, 1994, 21″ x 15″, Museum purchase funded by the Auxiliary of the Art Museum of South Texas
- La Sonrisa (The Smile) – George Molnar, A Better Place, oil on canvas, n.d., 11″ x 14″, Gift of Mary Grace and Frank P. Horlock
- El Telefono (The Telephone) – Daniel Blagg, Pay Phone, oil on canvas, 1988, 60″ x 90″
- El Toro (The Bull) – Sheri Emerick, digital photo, 2018
- El Valiente (The Brave) – Dave McGar, Iron That Walks, bronze with patina and paint, 1991, 33.5″ x 18″ x 11.5″, Gift of Mary Grace and Frank P. Horlock
- La Vaquita (The Little Cow) – Andy Warhol, Cow, serigraph, 1971, 45.75″ x 28.5″, Museum purchase funded by the Corpus Christi Art Foundation
- El Vidrio (The Glass) – Dale Chihuly, Blue Cascade Cohn Chandelier, blown glass, 1999, 72″ x 60″, Gift of Francine and Marc Cohn